Anxiolytic and sedative properties of hydroethanolic extract of Telfairia occidentalis leaves in mice

Anxiolytic and sedative properties of hydroethanolic extract of Telfairia occidentalis leaves in mice

Telfairia occidentalis Hook. f., Cucurbitaceae, is a leafy vegetable used in soup and folk medicine in southern Nigeria. This study was conducted to investigate the anxiolytic and sedative activities of the hydroethanolic extract of the leaves of T. occidentalis in mice. The hole-board, elevated plus maze, open-field, light-dark, and social interaction tests were used in this study. T. occident...

Pharmacological Evaluation of Sedative activity of methanolic extract of Thuja occidentalis in mice.

The methanolic leaf extract of Thuja occidentalis was evaluated for possible sedative activities in mice. Sedative activity was evaluated by using hole cross, open field, thiopental sodium-induced sleeping time and elevated-plus maze (EPM) tests at 200mg/kg and 400 mg/kg.  The extract decreased the locomotor activity of mice in hole cross, open field and EPM test and showed the remarka...

Pharmacological Evaluation of Sedative activity of methanolic extract of Thuja occidentalis in mice.

The methanolic leaf extract of Thuja occidentalis was evaluated for possible sedative activities in mice. Sedative activity was evaluated by using hole cross, open field, thiopental sodium-induced sleeping time and elevated-plus maze (EPM) tests at 200mg/kg and 400 mg/kg.  The extract decreased the locomotor activity of mice in hole cross, open field and EPM test and showed the remarka...

Sub-Chronic Toxicity of the Hydroethanolic Leaf Extract of Telfairia occidentalis Hook. f. (Cucurbitaceae) in Male Rats

Background: Due to its nutritional and medicinal values, the leaf of Telfairia occidentalis Hook f. (Cucurbitaceae) is consumed in different parts of Nigeria. Acute and sub-chronic toxicity of the hydroethanolic leaf extract of Telfairiaoccidentalis were investigated in this study. Methods: Sixty-four male rats were randomized into four different groups of 16 animals each and were separately ad...

Erythrocytotoxic Effects of Telfairia occidentalis Leaves Extract: Results of an In Vitro Phytotoxicity Study on Human Erythrocytes